Oct 6, 2020 11:12
3 yrs ago
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English term

Cell based VEGF stimulated VEGFR reporter assay

English to Russian Science Biology (-tech,-chem,micro-)
The results of a cell-based VEGF stimulated VEGFR reporter assay are provided in Table 2.

Under the conditions tested the inhibitor molecule inhibited VEGF stimulated VEGFR reporter cells with IC50 values of...

Спасибо!

Discussion

liz askew Oct 6, 2020:
oh, I see "R" = receptor
liz askew Oct 6, 2020:
sorry, I meant
in "VEGF"!
liz askew Oct 6, 2020:
does the "R" in "VGFR" stand for "responsive"?
Abstract Introduction Conclusion Methods - Mynewsdeskwww.mynewsdesk.com › material › document › downloadPDF
A novel highly sensitive ***VEGF-responsive reporter gene assay***has been developed that allows bevacizumab activity to be quantified rapidly and in a highly ...

Proposed translations

22 hrs
Selected

репортерный анализ VEGF-опосредованной стимуляции [рецептора] VEGFR в клеточной системе

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4 KudoZ points awarded for this answer. Comment: "Спасибо, Игорь"

Reference comments

3 hrs
Reference:

comments

trouble is that the English is totally unclear

However findings:

VEGF-A binds to and activates both VEGFR-1 and VEGFR-2, promoting angiogenesis, vascular permeability, cell migration, and gene expression. In addition, Lee et al. showed that an autocrine loop of VEGF-A and its receptor system exist within vascular endothelial cells, contributing to endothelial functions.

so perhaps VEGF-activated VEGFR

would make more sense

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Note added at 3 hrs (2020-10-06 14:24:35 GMT)
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also

another finding, which may help with parsing

***Cell Based Reporter Assays***

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Note added at 3 hrs (2020-10-06 14:37:40 GMT)
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so

VEGF-activated VEGFR cell based reporter assay
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