Jul 23, 2018 06:35
5 yrs ago
1 viewer *
English term
bar for acceptance
English to French
Medical
Medical (general)
Product\'s indication and inclusion on formulary
Not so sure about this one… it's asking about the indication that would have the highest bar for acceptance… Would it be the one indication least likely to be accepted?
Proposed translations
(French)
Proposed translations
-2
21 hrs
English term (edited):
the indication that would have the highest bar for acceptance
Selected
l'indication qui aurait le plus haut seuil d'acceptation pour inclusion dans la pharmacopée
to make any sense of it, you have to look at the whole of:
"the indication that would have the highest bar for acceptance"
l'indication qui aurait le plus haut seuil d'acceptation pour l'inclusion dans la pharmacopée (/la liste des médicaments autorisés)
first point: "bar" here has nothing to do with "barring" (=interdiction)
it's about "setting the bar (to jump over) high" i.e. having more exacting requirements, setting goals more difficult to achieve,
as in: in you set the bar low enough you are guaranteed to "succeed" (sarcasm intended)
any medicine would be approved ONLY for some specific "indications" = authorised use only for some conditions (which still doesn't stop the "off label" use - i.e. not for approved/authorised indications)
so if this medicine has potentially several "indications" i.e. potential uses, the questions is:
for which indication is the bar set the highest
i.e for which indication it will be the most difficult to get an approval / to get the medicine approved to be used for that indication
If the context is as given:
Product's indication and inclusion on formulary
you have to take into account what is a "formulary" of drugs/medicines
What is formulary drugs vs non formulary?
Formularies are lists that have the insurance carriers preferred drugs. You can normally find both generic and brand name drugs in the formularies. Formulary prescription drugs are chosen for their cost, effectiveness, and their safety. Non-formulary drugs will cost the member more money than formularies.
http://www.biabenefit.com/formulary-versus-non-formulary-pre...
https://en.wikipedia.org/wiki/Formulary_(pharmacy)
http://www.selondonjointmedicinesformulary.nhs.uk/
https://en.wikipedia.org/wiki/Pharmacopoeia
https://fr.wikipedia.org/wiki/Pharmacopée
so it's not "approval for use" in the sense of "marketing authorisation" but in the sense of the medicine being included of not in a "formulary" (which one? missing context ...) IOW the drug is legal to use (has the "marketing authorisation") but may or may not be included in some "formulary", or may not be included for all indications that are included in it's "marketing authorisation".
all this assuming that the question in the ST is EXACTLY about:
"the indication that would have the highest bar for acceptance" in a formulary
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Note added at 21 hrs (2018-07-24 04:13:09 GMT)
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Répertoire des médicaments
http://ansm.sante.fr/Services/Repertoire-des-medicaments
"the indication that would have the highest bar for acceptance"
l'indication qui aurait le plus haut seuil d'acceptation pour l'inclusion dans la pharmacopée (/la liste des médicaments autorisés)
first point: "bar" here has nothing to do with "barring" (=interdiction)
it's about "setting the bar (to jump over) high" i.e. having more exacting requirements, setting goals more difficult to achieve,
as in: in you set the bar low enough you are guaranteed to "succeed" (sarcasm intended)
any medicine would be approved ONLY for some specific "indications" = authorised use only for some conditions (which still doesn't stop the "off label" use - i.e. not for approved/authorised indications)
so if this medicine has potentially several "indications" i.e. potential uses, the questions is:
for which indication is the bar set the highest
i.e for which indication it will be the most difficult to get an approval / to get the medicine approved to be used for that indication
If the context is as given:
Product's indication and inclusion on formulary
you have to take into account what is a "formulary" of drugs/medicines
What is formulary drugs vs non formulary?
Formularies are lists that have the insurance carriers preferred drugs. You can normally find both generic and brand name drugs in the formularies. Formulary prescription drugs are chosen for their cost, effectiveness, and their safety. Non-formulary drugs will cost the member more money than formularies.
http://www.biabenefit.com/formulary-versus-non-formulary-pre...
https://en.wikipedia.org/wiki/Formulary_(pharmacy)
http://www.selondonjointmedicinesformulary.nhs.uk/
https://en.wikipedia.org/wiki/Pharmacopoeia
https://fr.wikipedia.org/wiki/Pharmacopée
so it's not "approval for use" in the sense of "marketing authorisation" but in the sense of the medicine being included of not in a "formulary" (which one? missing context ...) IOW the drug is legal to use (has the "marketing authorisation") but may or may not be included in some "formulary", or may not be included for all indications that are included in it's "marketing authorisation".
all this assuming that the question in the ST is EXACTLY about:
"the indication that would have the highest bar for acceptance" in a formulary
--------------------------------------------------
Note added at 21 hrs (2018-07-24 04:13:09 GMT)
--------------------------------------------------
Répertoire des médicaments
http://ansm.sante.fr/Services/Repertoire-des-medicaments
Peer comment(s):
| disagree |
GILLES MEUNIER
: ça ne veut pas dire grand chose et c'est une formulation lourde au niveau du style
3 hrs
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| disagree |
Drmanu49
: Surtraduction et pas bien différent de mon interpretation.
16 hrs
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well, there is a significant difference in the implied context. Plus I didn't mention ANYTHING even remotely linked to "compliance" nor "rates of adherence to the treatment by patients".
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4 KudoZ points awarded for this answer.
Comment: "Clairement LA réponse où le sens est le plus clairement transposé… puisqu'il ne s'agit pas d'observance, ni de norme d'acceptation, ni d'obstacle… "
-1
10 mins
constituerait l'obstacle le plus important à l'acceptation
..
5 hrs
le plus haut niveau de compliance/observance ou le meilleur taux d'acceptation
IMO
Observance - Académie Nationale de Pharmacie
www.acadpharm.org/.../Rapport_l_observance_mEdicamenteuse_V...
Observance des traitements médicamenteux en France ». Rapport ...... I.1 Définitions, termes utilisés : observance, compliance, adhérence ..... semblent toutes montrer une meilleure efficacité pour les niveaux les plus élevés d'observance39.
Observance - Académie Nationale de Pharmacie
www.acadpharm.org/.../Rapport_l_observance_mEdicamenteuse_V...
Observance des traitements médicamenteux en France ». Rapport ...... I.1 Définitions, termes utilisés : observance, compliance, adhérence ..... semblent toutes montrer une meilleure efficacité pour les niveaux les plus élevés d'observance39.
Peer comment(s):
| agree |
GILLES MEUNIER
16 hrs
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Thank you Gilles.
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| disagree |
Daryo
: doesn't fit with the rest of the ST // As far as I can see this ST is about including a drug in some formulary, not about patients adhering or not to a treatment.
1 day 5 hrs
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It sure does and why suggest a very similar answer?
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9 hrs
la limite la plus élevée (supérieure) de la norme d'acceptation
ou la limite supérieure de la norme d'acceptation
Discussion
As for "une formule allégée et digeste" unless you start just chucking out bits of the ST, I can't anything shorter than what I proposed. Nice style is fine - as long it's accurate.
but this question would make sense only for a medicine has more than one indication, and someone (who? the manufacturer? some Ministry of Health? ...) is considering including it in some "formulary" (again, which one? a national formulary? a formulary used by some health insurance company? ...) and some indications for that drug are easier to have included in this "formulary", and some other indications are more difficult to have in included in this "formulary".
For a medicine with only one indication this question would be totally pointless.
The question is asking which indications have a higher bar for acceptance.
I would tend to go with the idea that this is refering to a threshold as, in this context, it seems unlikely that an indication would prevent ahe drug's acceptance on the formular...
We don't know if 'bar' means 'soemthing that prevents', or instead, 'a threshold' — cf. 'setting the bar too high'
The surrounding text doesn't help much: the use of 'highest' suggests possible the 'threshold' idea — we'd probably be more likely to say 'the greatest' if it were 'prevents'. Likewise, 'bar for acceptance' seems to suggest a threshold for something to be accepted, otherwise they might well have written a 'bar to acceptance'. And also, the use of 'indication' is usually a positive thing — 'when it is useful to use this medicine', so if it were something that prevents, i'd have expecetd it to be 'contra-indication', for example.
I think more of your surrounding context will immediately clear up this ambiguity.