Glossary entry (derived from question below)
английский term or phrase:
APC
русский translation:
Aminopentane carboxylic acid
Added to glossary by
Anastasia Serdyukova
May 2, 2013 11:34
11 yrs ago
английский term
APC
английский => русский
Медицина
Медицина: Фармацевтика
The effects of such anticonvulsant drugs was reflected by a decrease in AUC of SN-38 and SN-38G by 50% or more.
In addition to induction of cytochrome P450 3A enzymes, enhanced glucuronidation and enhanced biliary excretion may play a role in reducing exposure to irinotecan and its metabolites.
A study has shown that the co-administration of ketoconazole resulted in a decrease in the AUC of APC of 87% and in an increase in the AUC of SN-38 of 109% in comparison to irinotecan given alone.
In addition to induction of cytochrome P450 3A enzymes, enhanced glucuronidation and enhanced biliary excretion may play a role in reducing exposure to irinotecan and its metabolites.
A study has shown that the co-administration of ketoconazole resulted in a decrease in the AUC of APC of 87% and in an increase in the AUC of SN-38 of 109% in comparison to irinotecan given alone.
Proposed translations
(русский)
4 | Aminopentane carboxylic acid | Alexander Vorobyev |
3 | дериват аминопентановой кислоты | olga_tr |
Proposed translations
24 мин
Selected
Aminopentane carboxylic acid
Один из метаболитов иринотекана. Должен фигурировать где-то еще в тексте.
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Note added at 43 мин (2013-05-02 12:18:22 GMT)
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http://dmd.aspetjournals.org/content/28/4/423.abstract
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Note added at 43 мин (2013-05-02 12:18:22 GMT)
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http://dmd.aspetjournals.org/content/28/4/423.abstract
4 KudoZ points awarded for this answer.
41 мин
английский term (edited):
APC
дериват аминопентановой кислоты
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